PKDREJ

Across TCGA pan-cancer cohorts, PKDREJ RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated PKDREJ data layer compared with 6 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher PKDREJ RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated PKDREJ expression acts as an unfavorable survival marker, although some lineages such as HNSC and KIRC show a favorable association.

HNSC, ACC, and KIRC are the cancer types where PKDREJ RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	All	0.782	0.602	<.001	81	view →
ACC	DFS	Quartile	All	0.477	0.873	<.001	69	view →
KIRC	DFS	Tertile	All	0.746	0.477	<.001	39	view →
UCS	DFS	Median	IV	0.952	0.367	.001	38	view →
PAAD	DFS	Quartile	II,III,IV	0.571	0.263	.001	32	view →
THYM	DFS	Tertile	III,IV	1.000	0.216	.006	28	view →
BLCA	DFS	Median	IV	0.112	0.341	.009	19	view →
KIRP	DFS	Median	All	0.901	0.597	.003	18	view →
COAD	DFS	Quartile	All	0.865	0.684	.004	16	view →
MESO	OS	Median	All	0.701	0.318	.009	16	view →
SCLC	DFS	Median	II,III,IV	0.759	0.264	.023	12	view →
LIHC	DFS	Tertile	All	0.479	0.606	.012	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

PKDREJ–HNSC (DFS)

Open the HNSC breakdown →