PKDCC

Across TCGA patient cohorts, PKDCC protein abundance is significantly associated with the RNA expression of many other genes, with 1,006 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PKDCC-associated genes across cancer lineages are SLC5A1, TXN2, and FOXRED2. Each is linked with PKDCC in more than 1 cancer types. Because this analysis shows association rather than direction, both PKDCC-to-partner and partner-to-PKDCC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PKDCC versus SLC5A1 in UCEC, with a Pearson correlation of 0.84.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PKDCC→partner) and Y-score (partner→PKDCC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SLC5A1 →	+3.370	+1.785	<.001	<.001	3	1
UCEC	TXN2 →	+1.295	+1.904	.002	.008	3	1
UCEC	FOXRED2 →	-0.995	-1.892	.007	.004	3	1
UCEC	PMM1 →	+1.406	+1.599	.008	.007	3	1
UCEC	ABHD4 →	+1.018	+1.785	.001	<.001	3	1
UCEC	FKBP3 →	+0.541	+1.785	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,006 associations by consensus.

PKDCC vs SLC5A1 — UCEC

Explore this scatter interactively →