PKDCC

Across TCGA cell cohorts, PKDCC RNA expression is significantly associated with the go_rna of many other GO terms, with 3,687 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PKDCC-associated GO terms across cancer lineages are Lung alveolus development, IMP salvage, and Monocarboxylic acid catabolic process. Each is linked with PKDCC in more than 8 cancer types. Because this analysis shows association rather than direction, both PKDCC-to-partner and partner-to-PKDCC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lung alveolus development grouped by PKDCC-low versus PKDCC-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PKDCC→partner) and Y-score (partner→PKDCC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Lung alveolus development →	+0.196	+1.764	<.001	.006	3	9
STOMACH	IMP salvage →	+0.262	+4.290	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Monocarboxylic acid catabolic process →	+0.094	+2.108	<.001	<.001	3	8
STOMACH	Positive regulation of chondrocyte differentiation →	+0.234	+3.516	.002	.003	3	8
STOMACH	Digestive system development →	+0.092	+3.797	.003	<.001	3	8
BREAST	Ribonucleoside triphosphate biosynthetic process →	+0.067	+2.056	.003	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,687 associations by consensus.

Lung alveolus development by PKDCC expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →