PKD2L1

Across TCGA cell cohorts, PKD2L1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,283 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PKD2L1-associated GO terms across cancer lineages are Extracellular matrix organization, Extracellular structure organization, and Organic cation transport. Each is linked with PKD2L1 in more than 4 cancer types. Because this analysis shows association rather than direction, both PKD2L1-to-partner and partner-to-PKD2L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Extracellular matrix organization grouped by PKD2L1-low versus PKD2L1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PKD2L1→partner) and Y-score (partner→PKD2L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Extracellular matrix organization →	-0.213	-0.174	<.001	.002	3	5
BONE	Extracellular structure organization →	-0.214	-0.174	<.001	.002	3	5
LIVER	Organic cation transport →	+0.129	+0.113	<.001	<.001	2	5
SOFT_TISSUE	Indole-containing compound metabolic process →	+0.106	+0.059	.001	.006	3	4
SOFT_TISSUE	Lipoprotein particle mediated signaling →	+0.170	+0.069	<.001	<.001	2	5
OVARY	Regulation of glycogen metabolic process →	+0.045	+0.044	.003	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,283 associations by consensus.

Extracellular matrix organization by PKD2L1 expression — BONE

Explore this box plot interactively →