PKD1L3

Across TCGA patient cohorts, PKD1L3 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,789 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PKD1L3-associated proteins across cancer lineages are SASH1_S743, GAB3_S371, and SEC63_T537. Each is linked with PKD1L3 in more than 3 cancer types. Because this analysis shows association rather than direction, both PKD1L3-to-partner and partner-to-PKD1L3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PKD1L3 versus SASH1_S743 in LSCC, with a Pearson correlation of 0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PKD1L3→partner) and Y-score (partner→PKD1L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SASH1_S743 →	+0.717	+0.214	<.001	.001	3	4
PDAC	GAB3_S371 →	+1.035	+0.244	<.001	<.001	3	4
LSCC	SEC63_T537 →	-0.901	-0.240	<.001	<.001	3	4
LSCC	MYBBP1A_S1267 →	-0.568	-0.158	<.001	.004	3	3
CCRCC	NIPBL_T2667 →	+0.383	+0.214	<.001	.001	3	3
HNSC	PIP4K2A →	+0.233	+0.388	.001	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,789 associations by consensus.

PKD1L3 vs SASH1_S743 — LSCC

Explore this scatter interactively →