PKD1L2

Across TCGA cell cohorts, PKD1L2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,598 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PKD1L2-associated GO terms across cancer lineages are Vacuolar transport, Establishment of protein localization to membrane, and Viral process. Each is linked with PKD1L2 in more than 10 cancer types. Because this analysis shows association rather than direction, both PKD1L2-to-partner and partner-to-PKD1L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vacuolar transport grouped by PKD1L2-low versus PKD1L2-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PKD1L2→partner) and Y-score (partner→PKD1L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Vacuolar transport →	+0.064	+1.434	<.001	<.001	3	11
BREAST	Establishment of protein localization to membrane →	+0.064	+1.445	<.001	.001	3	10
OESOPHAGUS	Viral process →	+0.090	+1.900	<.001	.009	3	10
BONE	Lysosomal transport →	+0.064	+0.898	.002	.005	3	10
BREAST	Regulation of pinocytosis →	+0.117	+1.374	<.001	<.001	3	9
BREAST	Negative regulation of transforming growth factor beta production →	+0.272	+1.461	<.001	.003	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,598 associations by consensus.

Vacuolar transport by PKD1L2 expression — SKIN

Explore this box plot interactively →