PKD1L1

Across TCGA cell cohorts, PKD1L1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,604 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PKD1L1-associated GO terms across cancer lineages are Detection of external stimulus, Detection of abiotic stimulus, and Response to starvation. Each is linked with PKD1L1 in more than 7 cancer types. Because this analysis shows association rather than direction, both PKD1L1-to-partner and partner-to-PKD1L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Detection of external stimulus grouped by PKD1L1-low versus PKD1L1-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PKD1L1→partner) and Y-score (partner→PKD1L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Detection of external stimulus →	-0.051	-0.144	.002	.003	3	8
LARGE_INTESTINE	Detection of abiotic stimulus →	-0.052	-0.148	.002	.002	3	8
STOMACH	Response to starvation →	+0.065	+0.204	<.001	.002	3	6
STOMACH	Regulation of postsynaptic membrane potential →	-0.110	-0.174	.002	.007	2	7
UPPER_AERODIGESTIVE_TRACT	Cytoskeleton-dependent cytokinesis →	+0.054	+0.112	.008	.006	3	6
STOMACH	Endosomal transport →	+0.077	+0.196	<.001	.003	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,604 associations by consensus.

Detection of external stimulus by PKD1L1 expression — LARGE_INTESTINE

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