Across TCGA patient cohorts, PJA2 mutation is significantly associated with the RNA expression of many other genes, with 2,998 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PJA2-associated genes across cancer lineages are SNORA10B, GAGE12H, and MIR4472-2. Each is linked with PJA2 in more than 2 cancer types. Because this analysis shows association rather than direction, both PJA2-to-partner and partner-to-PJA2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PJA2→partner) and Y-score (partner→PJA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SNORA10B →	+0.906	+4.693	<.001	.007	3	3
SKCM	GAGE12H →	+0.689	+3.508	<.001	.006	3	3
BLCA	MIR4472-2 →	+0.578	+4.691	<.001	.001	3	2
SKCM	MTND5P9 →	+0.011	+4.147	<.001	.008	3	2
UCEC	MIR7976 →	+0.252	+1.737	.003	.008	3	2
COAD	MTND5P27 →	+0.156	+5.917	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,998 associations by consensus.

Exploration

PJA2 survival (RNA) · tumor vs normal (RNA) · all PJA2 data types