Across TCGA cell cohorts, PJA2 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PJA2-associated genes across cancer lineages are ZP2, MYL2, and IFNG. Each is linked with PJA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PJA2-to-partner and partner-to-PJA2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PJA2→partner) and Y-score (partner→PJA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ZP2 →	+0.179	+4.409	<.001	.005	3	1
BLOOD_Leukemia	MYL2 →	+0.572	+4.152	<.001	.009	3	1
BLOOD_Leukemia	IFNG →	+0.228	+4.152	<.001	.009	3	1
BLOOD_Leukemia	ZIC3 →	+0.019	+5.060	<.001	.001	3	1
BLOOD_Leukemia	KRTAP17-1 →	+0.695	+5.060	.007	.001	3	1
BLOOD_Leukemia	CFHR2 →	+0.296	+4.539	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

PJA2 survival (RNA) · tumor vs normal (RNA) · all PJA2 data types