Across TCGA cell cohorts, PIWIL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,218 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PIWIL2-associated GO terms across cancer lineages are Germ-line stem cell population maintenance, piRNA-mediated gene silencing by mRNA destabilization, and Cold acclimation. Each is linked with PIWIL2 in more than 13 cancer types. Because this analysis shows association rather than direction, both PIWIL2-to-partner and partner-to-PIWIL2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PIWIL2→partner) and Y-score (partner→PIWIL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Germ-line stem cell population maintenance →	+0.425	+0.454	<.001	<.001	3	14
LARGE_INTESTINE	piRNA-mediated gene silencing by mRNA destabilization →	-0.368	-0.915	<.001	<.001	3	9
PANCREAS	Cold acclimation →	+0.124	+0.281	.001	.002	3	5
STOMACH	Plasmacytoid dendritic cell activation →	-0.227	-1.413	<.001	.005	3	5
BLOOD_Lymphoma	Positive regulation of amyloid fibril formation →	+0.186	+0.403	<.001	.004	3	5
BLOOD_Lymphoma	Regulation of immune response to tumor cell →	+0.072	+0.321	<.001	.008	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,218 associations by consensus.

Exploration

PIWIL2 survival (RNA) · tumor vs normal (RNA) · all PIWIL2 data types