PITPNM3

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PITPNM3 protein abundance is significantly associated with the RNA expression of many other genes, with 4,437 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PITPNM3-associated genes across cancer lineages are CSTB, MFSD4A, and DOCK9. Each is linked with PITPNM3 in more than 3 cancer types. Because this analysis shows association rather than direction, both PITPNM3-to-partner and partner-to-PITPNM3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PITPNM3 versus CSTB in UCEC, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PITPNM3→partner) and Y-score (partner→PITPNM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCSTB →+1.201+0.572<.001<.00133
LUADMFSD4A →+1.454+0.423<.001<.00133
GBMDOCK9 →+0.605+0.331<.001<.00133
GBMEPB41L4B →+0.713+0.245.003.00924
HNSCMAP3K14 →-0.594-0.482.002.00333
LSCCTRIM2 →+0.954+0.479.001.00233
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,437 associations by consensus.

PITPNM3 vs CSTB — UCEC

Per-sample scatter of PITPNM3 vs CSTB in UCEC (Pearson r = 0.44).

Explore this scatter interactively →

Exploration