PITPNM3

Across TCGA cell cohorts, PITPNM3 mutation is significantly associated with the RNA expression of many other genes, with 446 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PITPNM3-associated genes across cancer lineages are OR2M4, PCDH11X, and ST8SIA2. Each is linked with PITPNM3 in more than 1 cancer types. Because this analysis shows association rather than direction, both PITPNM3-to-partner and partner-to-PITPNM3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2M4 grouped by PITPNM3-low versus PITPNM3-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PITPNM3→partner) and Y-score (partner→PITPNM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	OR2M4 →	+0.016	+4.029	<.001	.007	3	2
PANCREAS	PCDH11X →	+0.094	+4.035	.003	.003	3	1
PANCREAS	ST8SIA2 →	+0.033	+4.035	.002	.003	3	1
PANCREAS	TMEFF2 →	+0.260	+4.035	<.001	.003	3	1
PANCREAS	CNTNAP5 →	+0.061	+4.035	.001	.003	3	1
PANCREAS	PABPC5 →	+0.131	+4.222	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 446 associations by consensus.

OR2M4 by PITPNM3 expression — PANCREAS

Explore this box plot interactively →