PITPNC1

Across TCGA patient cohorts, PITPNC1 mutation is significantly associated with the RNA expression of many other genes, with 1,908 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PITPNC1-associated genes across cancer lineages are RN7SKP247, MIR6780A, and RPL31P1. Each is linked with PITPNC1 in more than 2 cancer types. Because this analysis shows association rather than direction, both PITPNC1-to-partner and partner-to-PITPNC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP247 grouped by PITPNC1-low versus PITPNC1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PITPNC1→partner) and Y-score (partner→PITPNC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SKP247 →	+0.293	+5.097	<.001	.008	3	3
LUSC	MIR6780A →	+0.796	+4.067	<.001	.001	3	3
LUAD	RPL31P1 →	+0.089	+5.279	.003	.006	3	2
BRCA	BRD9P1 →	+0.069	+6.215	<.001	.001	3	2
HNSC	OR4F8P →	+0.039	+7.954	<.001	.008	3	2
LUSC	OR6K6 →	+0.059	+4.792	.003	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,908 associations by consensus.

RN7SKP247 by PITPNC1 expression — SKCM

Explore this box plot interactively →