PITPNB

Across TCGA patient cohorts, PITPNB protein abundance is significantly associated with the RNA expression of many other genes, with 9,089 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PITPNB-associated genes across cancer lineages are UBE2L3, DRG1, and ASCC2. Each is linked with PITPNB in more than 5 cancer types. Because this analysis shows association rather than direction, both PITPNB-to-partner and partner-to-PITPNB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PITPNB versus UBE2L3 in LSCC, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PITPNB→partner) and Y-score (partner→PITPNB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	UBE2L3 →	+0.423	+0.207	<.001	<.001	3	6
GBM	DRG1 →	+0.423	+0.332	<.001	<.001	3	5
HNSC	ASCC2 →	+0.406	+0.232	.003	.005	3	5
LSCC	EIF3D →	+0.358	+0.164	<.001	<.001	3	5
LSCC	PES1 →	+0.426	+0.192	<.001	<.001	3	4
BRCA	SRRD →	+0.498	+0.380	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,089 associations by consensus.

PITPNB vs UBE2L3 — LSCC

Explore this scatter interactively →