PITPNB

Across TCGA cell cohorts, PITPNB RNA expression is significantly associated with the go_rna of many other GO terms, with 3,767 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PITPNB-associated GO terms across cancer lineages are Spindle elongation, Positive regulation of chromosome segregation, and Negative regulation of cell cycle process. Each is linked with PITPNB in more than 14 cancer types. Because this analysis shows association rather than direction, both PITPNB-to-partner and partner-to-PITPNB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Spindle elongation grouped by PITPNB-low versus PITPNB-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PITPNB→partner) and Y-score (partner→PITPNB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Spindle elongation →	+0.210	+0.810	<.001	.002	3	15
CNS	Positive regulation of chromosome segregation →	+0.119	+0.556	<.001	<.001	3	15
OVARY	Negative regulation of cell cycle process →	+0.057	+0.792	.001	<.001	3	13
KIDNEY	Regulation of mitotic cytokinesis →	+0.094	+0.534	.001	.002	3	12
BREAST	Regulation of mitotic sister chromatid separation →	+0.109	+0.737	<.001	<.001	3	12
OVARY	Import into nucleus →	+0.057	+0.894	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,767 associations by consensus.

Spindle elongation by PITPNB expression — OVARY

Explore this box plot interactively →