PITPNA-AS1

Across TCGA pan-cancer cohorts, PITPNA-AS1 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated PITPNA-AS1 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher PITPNA-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PITPNA-AS1 expression acts as an unfavorable survival marker, although some lineages such as ESCA and UVM show a favorable association.

KICH, ACC, and LIHC are the cancer types where PITPNA-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Median	All	0.672	0.977	<.001	98	view →
ACC	DFS	Tertile	All	0.175	0.715	<.001	71	view →
LIHC	OS	Median	All	0.712	0.837	<.001	44	view →
KIRC	DFS	Median	IV	0.503	0.740	.005	22	view →
MESO	DFS	Tertile	IV	0.160	0.623	.008	21	view →
SKCM	DFS	Tertile	III,IV	0.456	0.749	.012	15	view →
ESCA	DFS	Median	All	0.922	0.451	.007	15	view →
UVM	DFS	Quartile	All	0.933	0.589	.008	12	view →
UCS	DFS	Tertile	II,III,IV	0.541	0.230	.039	12	view →
COAD	DFS	Tertile	All	0.480	0.691	.008	11	view →
HNSC	DFS	Quartile	All	0.276	0.504	.003	11	view →
BRCA	OS	Tertile	IV	0.772	0.189	.006	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

PITPNA-AS1–KICH (DFS)

Open the KICH breakdown →