PIPSL

Across TCGA patient cohorts, PIPSL RNA expression is significantly associated with the protein abundance of many other proteins, with 16,190 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PIPSL-associated proteins across cancer lineages are VEZF1, RPRD2, and RBMX_S88. Each is linked with PIPSL in more than 4 cancer types. Because this analysis shows association rather than direction, both PIPSL-to-partner and partner-to-PIPSL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIPSL versus VEZF1 in GBM, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PIPSL→partner) and Y-score (partner→PIPSL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	VEZF1 →	+0.399	+0.303	<.001	<.001	3	5
HNSC	RPRD2 →	+0.269	+0.694	<.001	<.001	3	5
GBM	RBMX_S88 →	+0.475	+0.502	<.001	<.001	3	5
LSCC	ARID4B →	+0.245	+0.553	<.001	<.001	3	5
GBM	ZFR →	+0.239	+0.346	<.001	<.001	3	4
GBM	ZNF638 →	+0.240	+0.328	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,190 associations by consensus.

PIPSL vs VEZF1 — GBM

Explore this scatter interactively →