PIP5KL1

Across TCGA patient cohorts, PIP5KL1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,022 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PIP5KL1-associated proteins across cancer lineages are GAPVD1, ICAM1, and TSPAN8. Each is linked with PIP5KL1 in more than 2 cancer types. Because this analysis shows association rather than direction, both PIP5KL1-to-partner and partner-to-PIP5KL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIP5KL1 versus GAPVD1 in LSCC, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PIP5KL1→partner) and Y-score (partner→PIP5KL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GAPVD1 →	+0.171	+0.546	<.001	<.001	3	3
LUAD	ICAM1 →	+0.514	+0.672	<.001	<.001	3	3
LUAD	TSPAN8 →	-1.199	-0.688	.003	.001	3	3
LSCC	U2SURP →	+0.245	+0.388	.001	.007	3	3
HNSC	RAB29 →	-0.470	-0.646	<.001	<.001	3	3
LSCC	STXBP5 →	-0.209	-0.436	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,022 associations by consensus.

PIP5KL1 vs GAPVD1 — LSCC

Explore this scatter interactively →