PIP5K1A

Across TCGA patient cohorts, PIP5K1A RNA expression is significantly associated with the protein abundance of many other proteins, with 16,039 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PIP5K1A-associated proteins across cancer lineages are IPO9, CDC73, and POGZ. Each is linked with PIP5K1A in more than 7 cancer types. Because this analysis shows association rather than direction, both PIP5K1A-to-partner and partner-to-PIP5K1A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIP5K1A versus IPO9 in LSCC, with a Pearson correlation of 0.58.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PIP5K1A→partner) and Y-score (partner→PIP5K1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	IPO9 →	+0.275	+0.537	<.001	<.001	3	8
COAD	CDC73 →	+0.321	+0.477	<.001	<.001	3	8
HNSC	POGZ →	+0.300	+0.549	<.001	<.001	3	7
LSCC	RPRD2 →	+0.307	+0.625	<.001	<.001	3	7
LUAD	ANP32E →	+0.563	+0.571	<.001	<.001	3	7
LSCC	GATAD2B →	+0.276	+0.443	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,039 associations by consensus.

PIP5K1A vs IPO9 — LSCC

Explore this scatter interactively →