PIP5K1A

Across TCGA patient cohorts, PIP5K1A protein abundance is significantly associated with the RNA expression of many other genes, with 4,672 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible PIP5K1A-associated genes across cancer lineages are TADA1, DARS2, and POGK. Each is linked with PIP5K1A in more than 4 cancer types. Because this analysis shows association rather than direction, both PIP5K1A-to-partner and partner-to-PIP5K1A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIP5K1A versus TADA1 in LSCC, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PIP5K1A→partner) and Y-score (partner→PIP5K1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TADA1 →	+0.446	+0.219	.001	.001	3	5
LUAD	DARS2 →	+0.635	+0.224	<.001	<.001	3	4
BRCA	POGK →	+0.559	+0.256	<.001	<.001	3	4
LSCC	PRUNE1 →	+0.637	+0.296	<.001	<.001	3	4
UCEC	ARNT →	+0.431	+0.258	.004	<.001	2	5
HNSC	POGZ →	+0.562	+0.193	.002	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,672 associations by consensus.

PIP5K1A vs TADA1 — LSCC

Explore this scatter interactively →