PIP4P2

Across TCGA patient cohorts, PIP4P2 mutation is significantly associated with the RNA expression of many other genes, with 1,590 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PIP4P2-associated genes across cancer lineages are MIR6803, MIR4752, and RN7SL326P. Each is linked with PIP4P2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PIP4P2-to-partner and partner-to-PIP4P2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6803 grouped by PIP4P2-low versus PIP4P2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PIP4P2→partner) and Y-score (partner→PIP4P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR6803 →	+0.130	+4.230	<.001	.004	3	2
UCEC	MIR4752 →	+0.107	+4.818	<.001	.001	3	2
LUSC	RN7SL326P →	+0.184	+4.652	.002	.004	3	2
LUAD	MIR4736 →	+0.444	+5.000	<.001	.003	3	2
LUAD	MIR6882 →	+0.597	+4.995	<.001	<.001	3	2
UCEC	RN7SL97P →	+0.133	+2.561	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,590 associations by consensus.

MIR6803 by PIP4P2 expression — UCEC

Explore this box plot interactively →