PIP4K2C

Across TCGA patient cohorts, PIP4K2C RNA expression is significantly associated with the protein abundance of many other proteins, with 10,249 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PIP4K2C-associated proteins across cancer lineages are LARP4, MYG1, and SPCS3. Each is linked with PIP4K2C in more than 4 cancer types. Because this analysis shows association rather than direction, both PIP4K2C-to-partner and partner-to-PIP4K2C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIP4K2C versus LARP4 in LUAD, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PIP4K2C→partner) and Y-score (partner→PIP4K2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	LARP4 →	+0.351	+0.535	<.001	<.001	3	5
BRCA	MYG1 →	+0.286	+0.458	<.001	<.001	3	5
LSCC	SPCS3 →	-0.563	-0.516	<.001	<.001	3	5
LSCC	CYSLTR1_S326 →	-0.955	-0.553	<.001	<.001	3	4
CCRCC	SH3KBP1_S183 →	-0.622	-0.336	<.001	<.001	3	4
CCRCC	SSR3_S105 →	-0.934	-0.287	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,249 associations by consensus.

PIP4K2C vs LARP4 — LUAD

Explore this scatter interactively →