PIP4K2C

Across TCGA cell cohorts, PIP4K2C RNA expression is significantly associated with the go_rna of many other GO terms, with 4,139 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PIP4K2C-associated GO terms across cancer lineages are Process utilizing autophagic mechanism, Autophagy, and Vacuolar transport. Each is linked with PIP4K2C in more than 15 cancer types. Because this analysis shows association rather than direction, both PIP4K2C-to-partner and partner-to-PIP4K2C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Process utilizing autophagic mechanism grouped by PIP4K2C-low versus PIP4K2C-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PIP4K2C→partner) and Y-score (partner→PIP4K2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Process utilizing autophagic mechanism →	+0.077	+1.114	.001	.002	3	16
STOMACH	Autophagy →	+0.077	+1.114	.001	.002	3	16
STOMACH	Vacuolar transport →	+0.084	+1.146	.001	.001	3	16
STOMACH	Lysosomal transport →	+0.081	+0.985	.004	.007	3	16
STOMACH	Endosomal transport →	+0.068	+1.004	.002	.006	3	15
STOMACH	Macroautophagy →	+0.078	+1.193	.001	.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,139 associations by consensus.

Process utilizing autophagic mechanism by PIP4K2C expression — STOMACH

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