PIP4K2B

Across TCGA patient cohorts, PIP4K2B RNA expression is significantly associated with the protein abundance of many other proteins, with 22,311 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PIP4K2B-associated proteins across cancer lineages are PCGF2, RPL6, and RRBP1. Each is linked with PIP4K2B in more than 5 cancer types. Because this analysis shows association rather than direction, both PIP4K2B-to-partner and partner-to-PIP4K2B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIP4K2B versus PCGF2 in BRCA, with a Pearson correlation of 0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PIP4K2B→partner) and Y-score (partner→PIP4K2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PCGF2 →	+0.439	+0.523	<.001	<.001	3	6
CCRCC	RPL6 →	-0.386	-0.287	<.001	<.001	3	6
LSCC	RRBP1 →	-0.369	-0.459	<.001	<.001	3	6
LSCC	HNRNPLL →	+0.223	+0.499	<.001	<.001	3	6
LSCC	ZNF638 →	+0.205	+0.513	<.001	<.001	3	5
GBM	MYDGF →	-0.326	-0.375	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,311 associations by consensus.

PIP4K2B vs PCGF2 — BRCA

Explore this scatter interactively →