PIP4K2B

Across TCGA cell cohorts, PIP4K2B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,992 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PIP4K2B-associated GO terms across cancer lineages are Regulation of nucleotide-excision repair, Epigenetic regulation of gene expression, and Heterochromatin organization. Each is linked with PIP4K2B in more than 16 cancer types. Because this analysis shows association rather than direction, both PIP4K2B-to-partner and partner-to-PIP4K2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of nucleotide-excision repair grouped by PIP4K2B-low versus PIP4K2B-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PIP4K2B→partner) and Y-score (partner→PIP4K2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of nucleotide-excision repair →	+0.171	+1.255	.001	.003	3	17
STOMACH	Epigenetic regulation of gene expression →	+0.073	+1.026	<.001	<.001	3	16
STOMACH	Heterochromatin organization →	+0.083	+1.076	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	DNA-templated transcription initiation →	+0.075	+0.897	<.001	.001	3	15
CNS	Positive regulation of gene expression, epigenetic →	+0.061	+0.592	<.001	<.001	3	15
KIDNEY	Regulation of autophagosome maturation →	+0.090	+0.852	<.001	.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,992 associations by consensus.

Regulation of nucleotide-excision repair by PIP4K2B expression — STOMACH

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