PINX1

Across TCGA patient cohorts, PINX1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,971 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PINX1-associated proteins across cancer lineages are CCAR2, XPO7, and MCPH1_S333. Each is linked with PINX1 in more than 8 cancer types. Because this analysis shows association rather than direction, both PINX1-to-partner and partner-to-PINX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PINX1 versus CCAR2 in OV, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PINX1→partner) and Y-score (partner→PINX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CCAR2 →	+0.442	+0.776	<.001	<.001	3	9
OV	XPO7 →	+0.300	+0.526	.002	.005	3	8
OV	MCPH1_S333 →	+0.826	+0.800	<.001	<.001	2	8
LSCC	RACGAP1 →	+0.766	+0.689	<.001	<.001	3	6
GBM	ADNP_S98 →	+0.803	+0.338	.001	.002	3	6
GBM	GINS3 →	+0.734	+0.329	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,971 associations by consensus.

PINX1 vs CCAR2 — OV

Explore this scatter interactively →