PINX1

Across TCGA patient cohorts, PINX1 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible PINX1-associated genes across cancer lineages are Adipocytes and Erythrocytes. Each is linked with PINX1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PINX1-to-partner and partner-to-PINX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Adipocytes grouped by PINX1-low versus PINX1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PINX1→partner) and Y-score (partner→PINX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Adipocytes →	+0.067	+3.030	<.001	.042	3	2
LUAD	Erythrocytes →	+0.033	+3.191	<.001	.031	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Adipocytes by PINX1 expression — COAD

Explore this box plot interactively →