Across TCGA patient cohorts, PIN4P1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,069 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible PIN4P1-associated proteins across cancer lineages are TPX2, TOP2A_S1377, and NCL_S67. Each is linked with PIN4P1 in more than 6 cancer types. Because this analysis shows association rather than direction, both PIN4P1-to-partner and partner-to-PIN4P1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PIN4P1→partner) and Y-score (partner→PIN4P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TPX2 →	+0.713	+0.892	<.001	<.001	3	7
LSCC	TOP2A_S1377 →	+0.951	+0.673	<.001	.002	3	7
LUAD	NCL_S67 →	+0.687	+0.474	.002	<.001	3	5
OV	PDS5A_T1208 →	+0.983	+1.281	<.001	<.001	3	5
GBM	SSRP1 →	+0.459	+0.676	.003	.001	3	5
OV	RPL12_S38 →	+1.008	+1.410	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,069 associations by consensus.

Exploration

PIN4P1 survival (RNA) · tumor vs normal (RNA) · all PIN4P1 data types