PIMREG

Across TCGA patient cohorts, PIMREG protein abundance is significantly associated with the RNA expression of many other genes, with 9,392 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PIMREG-associated genes across cancer lineages are FAM136A, OIP5, and FANCD2. Each is linked with PIMREG in more than 3 cancer types. Because this analysis shows association rather than direction, both PIMREG-to-partner and partner-to-PIMREG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIMREG versus FAM136A in LSCC, with a Pearson correlation of 0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PIMREG→partner) and Y-score (partner→PIMREG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	FAM136A →	+0.573	+0.732	<.001	<.001	3	4
UCEC	OIP5 →	+2.136	+1.276	.003	.001	3	4
UCEC	FANCD2 →	+2.070	+1.109	<.001	.008	3	4
UCEC	GEN1 →	+1.243	+1.276	<.001	.001	3	4
LUAD	CENPA →	+1.378	+0.734	.006	.006	2	4
LUAD	KIF11 →	+1.214	+0.734	.008	.006	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,392 associations by consensus.

PIMREG vs FAM136A — LSCC

Explore this scatter interactively →