PILRB

Across TCGA patient cohorts, PILRB protein abundance is significantly associated with the RNA expression of many other genes, with 99 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PILRB-associated genes across cancer lineages are HELLS, DMRTB1, and C1orf131. Each is linked with PILRB in more than 1 cancer types. Because this analysis shows association rather than direction, both PILRB-to-partner and partner-to-PILRB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PILRB versus HELLS in GBM, with a Pearson correlation of 0.82.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PILRB→partner) and Y-score (partner→PILRB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	HELLS →	+0.823	+1.043	.002	.001	3	1
GBM	DMRTB1 →	+0.055	+1.083	<.001	<.001	3	1
GBM	C1orf131 →	+0.215	+1.043	.009	.001	3	1
GBM	IGFN1 →	+1.681	+1.112	.007	.005	3	1
GBM	RNU105C →	+0.600	+0.846	.001	.004	3	1
GBM	RNU6ATAC5P →	+0.893	+0.846	.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 99 associations by consensus.

PILRB vs HELLS — GBM

Explore this scatter interactively →