PILRB

Across TCGA pan-cancer cohorts, PILRB RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of PILRB’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where PILRB RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PILRB is over-expressed in tumor.

COAD, HNSC, and KIRC are the cancer types where PILRB tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PILRB RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	II,III,IV	+1.124	<.001	10	view →
HNSC	Male	III,IV	+0.936	<.001	8	view →
KIRC	Male	All	+0.646	<.001	8	view →
STAD	All	II,III,IV	+0.870	<.001	7	view →
LIHC	All	All	+0.515	<.001	7	view →
BLCA	All	All	+0.666	.004	5	view →
ESCA	All	All	+0.937	.007	4	view →
LUSC	All	All	+0.583	<.001	4	view →
READ	All	All	+1.205	.003	3	view →
CHOL	All	All	+1.621	.003	2	view →
UCEC	All	All	+0.416	.041	2	view →
LUAD	All	All	+0.361	.017	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

PILRB–COAD

Open the COAD breakdown →