PILRB

Across TCGA patient cohorts, PILRB mutation is significantly associated with the RNA expression of many other genes, with 983 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PILRB-associated genes across cancer lineages are RNU6-13P, RNA5SP413, and ZNF101P1. Each is linked with PILRB in more than 2 cancer types. Because this analysis shows association rather than direction, both PILRB-to-partner and partner-to-PILRB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-13P grouped by PILRB-low versus PILRB-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PILRB→partner) and Y-score (partner→PILRB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-13P →	+0.272	+2.384	.001	.002	3	3
LUSC	RNA5SP413 →	+1.527	+5.666	<.001	<.001	3	3
KIRP	ZNF101P1 →	+0.082	+4.318	<.001	.007	3	3
LUSC	MMADHCP1 →	+0.256	+3.937	<.001	.007	3	2
HNSC	RN7SL623P →	+0.105	+4.578	<.001	.008	3	2
SKCM	ACTG1P13 →	+0.038	+3.116	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 983 associations by consensus.

RNU6-13P by PILRB expression — UCEC

Explore this box plot interactively →