PILRB

Across TCGA cell cohorts, PILRB mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PILRB-associated genes across cancer lineages are MOGAT1, H1-1, and ANKRD30BL. Each is linked with PILRB in more than 1 cancer types. Because this analysis shows association rather than direction, both PILRB-to-partner and partner-to-PILRB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MOGAT1 grouped by PILRB-low versus PILRB-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PILRB→partner) and Y-score (partner→PILRB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MOGAT1 →	+0.042	+4.037	<.001	.004	3	1
BLOOD_Leukemia	H1-1 →	+0.098	+4.037	<.001	.004	3	1
BLOOD_Leukemia	ANKRD30BL →	+1.083	+3.874	<.001	.005	3	1
BLOOD_Leukemia	GABRB1 →	+0.560	+3.722	<.001	.009	3	1
BLOOD_Leukemia	RPL10L →	+0.028	+3.874	<.001	.005	3	1
BLOOD_Leukemia	SMIM23 →	+0.018	+4.984	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

MOGAT1 by PILRB expression — BLOOD_Leukemia

Explore this box plot interactively →