PIK3R6

Across TCGA patient cohorts, PIK3R6 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,252 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PIK3R6-associated proteins across cancer lineages are MYO1F, MYO1G, and NCF2. Each is linked with PIK3R6 in more than 9 cancer types. Because this analysis shows association rather than direction, both PIK3R6-to-partner and partner-to-PIK3R6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIK3R6 versus MYO1F in GBM, with a Pearson correlation of 0.72.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PIK3R6→partner) and Y-score (partner→PIK3R6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MYO1F →	+0.729	+0.828	<.001	<.001	3	10
GBM	MYO1G →	+0.661	+0.756	<.001	<.001	3	10
UCEC	NCF2 →	+0.758	+0.765	<.001	<.001	3	10
GBM	NCF4 →	+0.612	+0.680	<.001	<.001	3	10
GBM	ARHGAP45 →	+0.644	+0.660	<.001	<.001	3	10
GBM	ARHGAP9 →	+0.592	+0.814	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,252 associations by consensus.

PIK3R6 vs MYO1F — GBM

Explore this scatter interactively →