PIK3CD

Across TCGA cell cohorts, PIK3CD RNA expression is significantly associated with the go_rna of many other GO terms, with 6,106 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible PIK3CD-associated GO terms across cancer lineages are Natural killer cell chemotaxis, Mast cell chemotaxis, and Mast cell migration. Each is linked with PIK3CD in more than 16 cancer types. Because this analysis shows association rather than direction, both PIK3CD-to-partner and partner-to-PIK3CD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Natural killer cell chemotaxis grouped by PIK3CD-low versus PIK3CD-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PIK3CD→partner) and Y-score (partner→PIK3CD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Natural killer cell chemotaxis →	+1.967	+2.136	<.001	<.001	3	17
KIDNEY	Mast cell chemotaxis →	+1.773	+1.858	<.001	<.001	3	15
KIDNEY	Mast cell migration →	+1.773	+1.858	<.001	<.001	3	15
SKIN	Neutrophil extravasation →	+1.930	+2.515	<.001	<.001	3	15
URINARY_TRACT	Protein depolymerization →	+0.124	+1.633	.002	.006	3	15
LUNG_NSCLC_LUSC	Actin filament depolymerization →	+0.249	+2.300	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,106 associations by consensus.

Natural killer cell chemotaxis by PIK3CD expression — KIDNEY

Explore this box plot interactively →