PIK3CD-AS1

Across TCGA pan-cancer cohorts, PIK3CD-AS1 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of PIK3CD-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where PIK3CD-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PIK3CD-AS1 is over-expressed in tumor, although a few such as LUSC and COAD show the opposite, repressed pattern.

KIRC, BRCA, and STAD are the cancer types where PIK3CD-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PIK3CD-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	IV	+0.254	<.001	12	view →
BRCA	All	All	+0.120	<.001	4	view →
STAD	All	II,III,IV	+0.344	.004	3	view →
KIRP	All	All	+0.101	.004	2	view →
LUSC	All	All	−0.111	.034	1	view →
THCA	Male	IV	+0.090	.023	1	view →
COAD	All	All	−0.061	.045	1	view →
BLCA	Male	IV	−0.045	.039	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

PIK3CD-AS1–KIRC

Open the KIRC breakdown →