PIK3CB

Across TCGA patient cohorts, PIK3CB protein abundance is significantly associated with the protein abundance of many other proteins, with 13,610 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PIK3CB-associated proteins across cancer lineages are TOMM70, UBA5, and DNAJC13. Each is linked with PIK3CB in more than 5 cancer types. Because this analysis shows association rather than direction, both PIK3CB-to-partner and partner-to-PIK3CB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIK3CB versus TOMM70 in CCRCC, with a Pearson correlation of 0.51.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PIK3CB→partner) and Y-score (partner→PIK3CB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	TOMM70 →	+0.318	+0.307	<.001	<.001	3	4
CCRCC	UBA5 →	+0.310	+0.261	<.001	<.001	3	4
PDAC	DNAJC13 →	+0.153	+0.150	.005	.009	1	6
CCRCC	FKBP7 →	-0.537	-0.370	<.001	<.001	3	4
HNSC	USP24 →	+0.184	+0.185	.002	.003	2	5
BRCA	ATP1A1 →	+0.520	+0.270	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,610 associations by consensus.

PIK3CB vs TOMM70 — CCRCC

Explore this scatter interactively →