PIK3AP1

Across TCGA patient cohorts, PIK3AP1 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,856 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PIK3AP1-associated proteins across cancer lineages are RCSD1, SASH3, and WAS. Each is linked with PIK3AP1 in more than 9 cancer types. Because this analysis shows association rather than direction, both PIK3AP1-to-partner and partner-to-PIK3AP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIK3AP1 versus RCSD1 in HNSC, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PIK3AP1→partner) and Y-score (partner→PIK3AP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RCSD1 →	+0.795	+1.194	<.001	<.001	3	10
GBM	SASH3 →	+0.655	+1.261	<.001	<.001	3	10
GBM	WAS →	+0.796	+1.318	<.001	<.001	3	10
HNSC	DOCK10 →	+0.524	+1.217	<.001	<.001	3	10
GBM	DOCK2 →	+0.817	+1.353	<.001	<.001	3	10
GBM	FMNL1 →	+0.759	+1.333	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,856 associations by consensus.

PIK3AP1 vs RCSD1 — HNSC

Explore this scatter interactively →