PIH1D2

Across TCGA cell cohorts, PIH1D2 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PIH1D2-associated genes across cancer lineages are FAM47A, KRTAP4-6, and KCNA10. Each is linked with PIH1D2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PIH1D2-to-partner and partner-to-PIH1D2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM47A grouped by PIH1D2-low versus PIH1D2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PIH1D2→partner) and Y-score (partner→PIH1D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	FAM47A →	+0.041	+4.922	<.001	.009	3	1
BLOOD_Leukemia	KRTAP4-6 →	+0.024	+5.201	.002	.006	3	1
BLOOD_Lymphoma	KCNA10 →	+0.016	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	OR4Q2 →	+0.013	+6.247	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

FAM47A by PIH1D2 expression — BLOOD_Leukemia

Explore this box plot interactively →