Q-omics provides the consensus-scored OR4Q2 profile across patient tissues and cancer cell-line models. OR4Q2 expression is associated with patient survival in 10 of 34 cancer types, with the highest sampling consensus in STAD. Additionally, OR4Q2 RNA expression shows 5,620 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight STAD as cancer lineages where OR4Q2 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes OR4Q2 survival associations across molecular data types. OR4Q2 RNA expression shows survival associations in the most cancer types (10). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

OR4Q2 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	10	STAD (93)	view →

This table ranks reproducible OR4Q2 RNA expression–survival associations across cancer types. High OR4Q2 expression shows unfavorable associations in STAD, BRCA, PAAD, READ, LUSC and PCPG. The STAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify STAD as the clearest survival context for OR4Q2 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Tertile	All	0.128	0.566	<.001	93	view →
BRCA	DFS	Tertile	II,III,IV	0.116	0.521	<.001	60	view →
PAAD	DFS	Tertile	II,III,IV	0.158	0.455	<.001	54	view →
READ	DFS	Tertile	IV	0.027	0.636	<.001	54	view →
LUSC	OS	Tertile	All	0.181	0.664	<.001	48	view →
PCPG	OS	Tertile	All	0.078	0.849	<.001	36	view →

Pink = unfavorable, green = favorable. all 10 lineages →

OR4Q2-STAD (OS)

Kaplan–Meier survival curve for OR4Q2 RNA expression in STAD: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with OR4Q2 in patient tissues and cancer cell lines. In patient samples, OR4Q2 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set. In cancer cell lines, OR4Q2 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in BLOOD_Lymphoma.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Function (RNA)	5,620	STAD (5299)	view →
RNA	4,314	COAD (1739)	view →

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	13	BLOOD_Lymphoma (13)	view →
Mutation	2	BLOOD_Lymphoma (2)	view →