PIH1D1

Across TCGA cell cohorts, PIH1D1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,712 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PIH1D1-associated GO terms across cancer lineages are snoRNA localization, Regulation of glucose mediated signaling pathway, and Positive regulation of glucose mediated signaling pathway. Each is linked with PIH1D1 in more than 14 cancer types. Because this analysis shows association rather than direction, both PIH1D1-to-partner and partner-to-PIH1D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, snoRNA localization grouped by PIH1D1-low versus PIH1D1-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PIH1D1→partner) and Y-score (partner→PIH1D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	snoRNA localization →	+0.075	+0.782	<.001	<.001	3	15
LIVER	Regulation of glucose mediated signaling pathway →	+0.130	+0.979	.002	<.001	3	14
LIVER	Positive regulation of glucose mediated signaling pathway →	+0.130	+0.979	.002	<.001	3	14
BONE	U4 snRNA 3'-end processing →	+0.178	+0.806	.002	.002	3	12
BONE	Positive regulation of DNA repair →	+0.082	+0.846	<.001	<.001	3	12
STOMACH	Negative regulation of mRNA splicing, via spliceosome →	+0.113	+0.829	.003	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,712 associations by consensus.

snoRNA localization by PIH1D1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →