PIGZ

Across TCGA patient cohorts, PIGZ protein abundance is significantly associated with the RNA expression of many other genes, with 1,703 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PIGZ-associated genes across cancer lineages are RNU6-429P, RBMX2, and C17orf64. Each is linked with PIGZ in more than 1 cancer types. Because this analysis shows association rather than direction, both PIGZ-to-partner and partner-to-PIGZ results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIGZ versus RNU6-429P in GBM, with a Pearson correlation of -0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PIGZ→partner) and Y-score (partner→PIGZ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RNU6-429P →	-1.245	-0.796	.002	<.001	3	2
PDAC	RBMX2 →	-0.530	-1.909	.008	<.001	3	1
PDAC	C17orf64 →	-0.241	-1.909	.002	<.001	3	1
PDAC	RPN1 →	-0.628	-1.909	.007	<.001	3	1
PDAC	RAB40C →	+0.333	+0.503	.003	.008	3	1
PDAC	RPS29P17 →	+1.223	+0.503	.006	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,703 associations by consensus.

PIGZ vs RNU6-429P — GBM

Explore this scatter interactively →