PIGR

Across TCGA patient cohorts, PIGR RNA expression is significantly associated with the RNA expression of many other genes, with 13,814 significant associations in total. ESCA shows the largest number of these associations.

The most reproducible PIGR-associated genes across cancer lineages are TNFSF13, CIITA, and CTSS. Each is linked with PIGR in more than 25 cancer types. Because this analysis shows association rather than direction, both PIGR-to-partner and partner-to-PIGR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIGR versus TNFSF13 in ESCA, with a Pearson correlation of 0.69.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PIGR→partner) and Y-score (partner→PIGR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	TNFSF13 →	+1.221	+4.978	<.001	<.001	3	26
LAML	CIITA →	+1.321	+0.236	<.001	<.001	3	25
UCS	CTSS →	+1.784	+2.936	<.001	.003	3	25
ESCA	LCN2 →	+3.159	+4.956	<.001	<.001	3	25
ESCA	LRG1 →	+1.664	+3.911	<.001	<.001	3	24
LAML	RBM47 →	+1.604	+0.244	<.001	<.001	3	23

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,814 associations by consensus.

PIGR vs TNFSF13 — ESCA

Explore this scatter interactively →