PIGR

Across TCGA patient cohorts, PIGR RNA expression is significantly associated with the protein abundance of many other proteins, with 17,224 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PIGR-associated proteins across cancer lineages are PIGR_S673, PIGR_S735, and PIGR_S682. Each is linked with PIGR in more than 8 cancer types. Because this analysis shows association rather than direction, both PIGR-to-partner and partner-to-PIGR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIGR versus PIGR_S673 in OV, with a Pearson correlation of 0.78.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PIGR→partner) and Y-score (partner→PIGR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PIGR_S673 →	+2.143	+2.109	<.001	<.001	3	9
OV	PIGR_S735 →	+3.460	+4.123	<.001	<.001	3	9
BRCA	PIGR_S682 →	+2.132	+4.898	.003	.001	3	8
LSCC	TJP3_S591 →	+0.768	+2.358	.004	<.001	3	7
LSCC	PIGR_S684 →	+3.238	+5.064	.004	.005	3	7
UCEC	TJP3 →	+0.464	+3.520	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,224 associations by consensus.

PIGR vs PIGR_S673 — OV

Explore this scatter interactively →