PIGPP4

Q-omics provides the consensus-scored PIGPP4 profile across patient tissues and cancer cell-line models. PIGPP4 expression is associated with patient survival in 13 of 34 cancer types, with the highest sampling consensus in MESO. Additionally, PIGPP4 RNA expression shows 6,135 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight MESO, and STAD as cancer lineages where PIGPP4 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes PIGPP4 survival associations across molecular data types. PIGPP4 RNA expression shows survival associations in the most cancer types (13). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

PIGPP4 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	13	MESO (126)	view →

This table ranks reproducible PIGPP4 RNA expression–survival associations across cancer types. High PIGPP4 expression shows unfavorable associations in MESO, LIHC, BLCA, THCA, ESCA and LUAD. The MESO Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify MESO as the clearest survival context for PIGPP4 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	IV	0.036	0.602	<.001	126	view →
LIHC	DFS	Tertile	All	0.068	0.531	<.001	87	view →
BLCA	DFS	Tertile	IV	0.139	0.476	<.001	45	view →
THCA	DFS	Tertile	II,III,IV	0.124	0.688	.002	36	view →
ESCA	OS	Tertile	All	0.198	0.872	.003	36	view →
LUAD	OS	Tertile	II,III,IV	0.004	0.751	<.001	36	view →

Pink = unfavorable, green = favorable. all 13 lineages →

PIGPP4-MESO (OS)

Explore this curve interactively →