Across TCGA patient cohorts, PIGP mutation is significantly associated with the RNA expression of many other genes, with 112 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PIGP-associated genes across cancer lineages are MIR4524B, IGLVI-42, and BPY2DP. Each is linked with PIGP in more than 1 cancer types. Because this analysis shows association rather than direction, both PIGP-to-partner and partner-to-PIGP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PIGP→partner) and Y-score (partner→PIGP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MIR4524B →	+0.543	+5.790	<.001	.003	3	2
BLCA	IGLVI-42 →	+0.084	+7.640	<.001	.009	3	1
COAD	BPY2DP →	+0.393	+7.409	<.001	<.001	3	1
COAD	MTND3P13 →	+0.221	+5.893	<.001	.002	3	1
COAD	ATP5MGP7 →	+0.227	+5.435	.003	.005	3	1
UCEC	LINC01050 →	+0.201	+2.287	.008	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 112 associations by consensus.

Exploration

PIGP survival (RNA) · tumor vs normal (RNA) · all PIGP data types