PIGO

Across TCGA patient cohorts, PIGO protein abundance is significantly associated with the RNA expression of many other genes, with 8,946 significant associations in total. COAD shows the largest number of these associations.

The most reproducible PIGO-associated genes across cancer lineages are LYL1, RASAL3, and ARHGAP9. Each is linked with PIGO in more than 5 cancer types. Because this analysis shows association rather than direction, both PIGO-to-partner and partner-to-PIGO results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIGO versus LYL1 in OV, with a Pearson correlation of -0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PIGO→partner) and Y-score (partner→PIGO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	LYL1 →	-0.724	-0.297	<.001	<.001	3	5
OV	RASAL3 →	-0.829	-0.354	<.001	<.001	3	5
OV	ARHGAP9 →	-0.643	-0.264	.004	.008	3	5
HNSC	MYO1F →	-0.687	-0.280	<.001	.002	3	5
UCEC	CD1D →	-0.662	-0.482	<.001	<.001	2	6
OV	CCR5 →	-0.897	-0.219	<.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,946 associations by consensus.

PIGO vs LYL1 — OV

Explore this scatter interactively →