PIGM

Across TCGA pan-cancer cohorts, PIGM mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated PIGM data layer compared with 23 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher PIGM mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated PIGM expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

UCEC, LSCC, and LUAD are the cancer types where PIGM mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Quartile	All	1.000	0.610	.016	10	view →
LSCC	OS	Tertile	III,IV	0.532	0.943	.010	8	view →
LUAD	DFS	Median	II,III,IV	0.215	0.781	.007	8	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

PIGM–UCEC (OS)

Open the UCEC breakdown →