PIGM

Across TCGA patient cohorts, PIGM RNA expression is significantly associated with the protein abundance of many other proteins, with 19,616 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PIGM-associated proteins across cancer lineages are DHX9, NAXE, and RPRD2. Each is linked with PIGM in more than 7 cancer types. Because this analysis shows association rather than direction, both PIGM-to-partner and partner-to-PIGM results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIGM versus DHX9 in LSCC, with a Pearson correlation of 0.62.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PIGM→partner) and Y-score (partner→PIGM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DHX9 →	+0.261	+0.692	<.001	<.001	3	8
PDAC	NAXE →	+0.396	+0.408	<.001	<.001	3	8
LSCC	RPRD2 →	+0.278	+0.598	<.001	<.001	3	7
LSCC	HNRNPU →	+0.269	+0.662	<.001	<.001	3	7
LSCC	BROX →	+0.402	+0.519	<.001	.003	3	7
GBM	RBMX →	+0.347	+0.348	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,616 associations by consensus.

PIGM vs DHX9 — LSCC

Explore this scatter interactively →