PIGM

Across TCGA cell cohorts, PIGM RNA expression is significantly associated with the go_rna of many other GO terms, with 4,231 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PIGM-associated GO terms across cancer lineages are Late viral transcription, Regulation of myoblast fusion, and Copper ion export. Each is linked with PIGM in more than 15 cancer types. Because this analysis shows association rather than direction, both PIGM-to-partner and partner-to-PIGM results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Late viral transcription grouped by PIGM-low versus PIGM-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PIGM→partner) and Y-score (partner→PIGM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Late viral transcription →	+0.137	+0.842	<.001	<.001	3	16
STOMACH	Regulation of myoblast fusion →	+0.150	+0.902	<.001	<.001	3	15
BLOOD_Leukemia	Copper ion export →	-0.205	-0.757	<.001	<.001	3	15
STOMACH	Regulation of syncytium formation by plasma membrane fusion →	+0.151	+1.044	<.001	<.001	3	14
STOMACH	Viral translational termination-reinitiation →	+0.101	+0.878	.002	<.001	3	14
OVARY	Negative regulation of myoblast fusion →	+0.122	+0.651	<.001	.002	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,231 associations by consensus.

Late viral transcription by PIGM expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →